University of Copenhagen
Institution / Head office:
Faculty of Natural Sciences
Summary:
SBiN has performed pioneering work on developing methods for the structure determination of proteins by NMR spectroscopy, determining one of the first 3D protein structures in the world.
Description:
The major expertise of the group is in protein interaction, structure and function relationships investigated by NMR spectroscopy as well as in biophysics. A hallmark of the research conducted in the group is a strong collaborative base with biology, medicine, and industry.
SBiN is concerned with several high priority key topics in natural sciences:
- The protein folding problem, such as the roles of intermediates and how the structure and thermodynamic properties of these states relate to protein aggregation and fibrillation
- Principles of protein function at the molecular and atomic level, such as understanding enzyme function and characterization of both enzyme and substrate/product structure and thermodynamics during catalysis
- Development of methods for molecular structure determination by NMR spectroscopy together with x-ray crystallography, protein engineering and biophysical techniques
- Development of methods for structure determination of membrane proteins in membrane mimetic solutions by NMR spectroscopy
Address:
Department of Biology
University of CopenhagenOle Maaløes Vej 52200 Copenhagen NDenmarkNavigation
